这是一个本地运行的 python 程序，依赖于 pyautogui 库进行自动化。核心的 trick 是使用 图像匹配的方式点击复选框。由于取关被限制每次只能选中20个，整个过程会重复多次进行。

import pyautogui as auto
from PIL import Image
import time

finished = False

checkbox = Image.open("checkbox-weibo.png")
cancel = Image.open("cancel-follow.png")
confirm = Image.open("confirm.png")

def click_image(image):
    loc = auto.locateCenterOnScreen(image, confidence=0.8)
    if loc is None: return False
    auto.moveTo(*loc, duration=0.1) # 移动鼠标
    auto.click(clicks=1) #点击
    return True

while not finished:

    for it in range(20):
        if not click_image(checkbox):
            finished = True
            break
        auto.hscroll(-400)

    auto.hscroll(400*(it)+1000)
    time.sleep(0.5)
    print("cancel:", click_image(cancel))
    time.sleep(0.5)
    print("confirm:", click_image(confirm))
    time.sleep(0.5)
    print("finished:", finished)